Epidemiology and natural history of HPV infection and cervical cancer
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چکیده
HPV vaccination of girls before their sexual debut is the best primary prevention method currently available. Incorporation of HPV vaccination in the public health sector is still to be seen in the developing world, mostly due to high vaccine cost. A significant HPV vaccination-induced reduction of cervical cancer burden is not likely to be evident for another 5 15 years. The best secondary prevention method is regular and adequate screening. New international and SA private sector guidelines propose the incorporation of molecular testing for HPV in screening and patient management, backed by good scientific evidence. It is transition time for screening programmes: a move from the annual Pap test to a new viral paradigm.
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